Molly Przeworski, Ph.D.
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Assistant Professor, Department of Human Genetics
B.A., Mathematics, Princeton University, 1994
Ph.D., Committee on Evolutionary Biology, University of Chicago, 2000
Postdoctoral researcher, Mathematical Genetics, University of Oxford, 2000-2001
920 E. 58th Street
CLSC 507H
Chicago, IL 60637
Phone: (773) 834-0525
Lab Phone: (773) 834-5909
Fax: (773) 834-0505
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My research focus is the population genetics of humans, particularly the genetic architecture of human-specific traits (adaptations or diseases) and the determinants of recombination rates. To address these sets of questions, my group combines modeling, the development of statistical tools and data analysis.
Selected Publications
Przeworski, M., Coop, G., and Wall, J. D. (2005). "The signature of positive selection on standing genetic variation." Evolution 59: 2312-2323.
Ptak, S. E., Roeder, A., Stephens, M., Gilad, Y., Paabo, S., and Przeworski, M. (2004). "Absence of the TAP2 human recombination hotspot in chimpanzees." PLoS Biology 2: 849-855.
Hellmann, I., Ebersberger, I., Ptak, S., Paabo, S. and Przeworski, M. (2003). "A neutral explanation for the correlation between diversity levels and recombination rates in humans." Am. J. Hum. Gen. 72: 1527-35.
Przeworski, M. (2002) "The signature of positive selection at randomly chosen loci." Genetics 160: 1179-1189.
Ptak, S., and Przeworski, M. (2002) "Evidence for population growth in humans is confounded by population structure." Trends in Gen. 18: 559-563.
Pritchard, J. K., and Przeworski, M. (2001) "Linkage disequilibrium in humans: models and data." Am. J. Hum. Gen. 68: 1-14.
Andolfatto, P., and Przeworski, M. (2000) "A genome-wide departure from the standard neutral model in natural populations of Drosophila." Genetics 155: 257-268.
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