2-locus haplotypes TDT in CSGA trios

Variation in the Interleukin 4-Receptor a Gene

Confers Susceptibility to Asthma and Atopy in
Ethnically Diverse Populations

P-values corresponding to global TDT analysis of
2-locus haplotypes, considering all possible pairs of loci
in the CSGA families.

Upper part of the table--results of analysis of atopy
Lower part of the table--results of analysis for asthma

Amino Acid 50 375 406 478 551

African Americans

50
>0.05 >0.05 >0.05 >0.05

375
>0.05 >0.05 >0.05 >0.05

406
>0.05 >0.05 >0.05 >0.05

478
0.022 >0.05 0.00018 >0.05

551
>0.05 >0.05 >0.05 >0.05

Caucasians

50
>0.05 >0.05 >0.05 >0.05

375
>0.05 0.020 0.014 >0.05

406
>0.05 >0.05 0.0044 >0.05

478
>0.05 >0.05 >0.05 >0.05

551
>0.05 >0.05 >0.05 >0.05 >0.05

Hispanics

375
. >0.05 >0.05 0.00093

406
0.037 >0.05 NI

478
0.025 0.024 0.016

551
0.0071 0.016 0.025

Index of IL4RA Gene results